[HTML][HTML] Lipids as conductors in the orchestra of life
CJR Loewen - F1000 biology reports, 2012 - ncbi.nlm.nih.gov
F1000 biology reports, 2012•ncbi.nlm.nih.gov
The lipid phosphatidic acid is an important metabolic intermediate in the biosynthesis of
lipids in all eukaryotic cells, but it is even more than that. Phosphatidic acid is emerging as a
lipid that is both composer and conductor, where in addition to its role as biosynthetic
precursor (composer) it is also a potent signaling molecule (conductor) that integrates
membrane biogenesis with nutrient sensing and cell growth. This article discusses recent
advances in yeast that give praise for phosphatidic acid as one of life's conductors.
lipids in all eukaryotic cells, but it is even more than that. Phosphatidic acid is emerging as a
lipid that is both composer and conductor, where in addition to its role as biosynthetic
precursor (composer) it is also a potent signaling molecule (conductor) that integrates
membrane biogenesis with nutrient sensing and cell growth. This article discusses recent
advances in yeast that give praise for phosphatidic acid as one of life's conductors.
Abstract
The lipid phosphatidic acid is an important metabolic intermediate in the biosynthesis of lipids in all eukaryotic cells, but it is even more than that. Phosphatidic acid is emerging as a lipid that is both composer and conductor, where in addition to its role as biosynthetic precursor (composer) it is also a potent signaling molecule (conductor) that integrates membrane biogenesis with nutrient sensing and cell growth. This article discusses recent advances in yeast that give praise for phosphatidic acid as one of life's conductors.
ncbi.nlm.nih.gov
